Reactome | ADH1A,1C,4 oxidise atROL to atRAL in vitro

Schema > Reaction > Entries

ADH1A,1C,4 oxidise atROL to atRAL in vitro Show undefined attributes

catalystActivity	[CatalystActivity:10789377] all-trans-retinol dehydrogenase (NAD+) activity of ADH1A,1C,4 dimers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10789379
displayName	ADH1A,1C,4 oxidise atROL to atRAL in vitro
eventOf	[Pathway:R-GGA-5365859] RA biosynthesis pathway - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-5362522] ALDHs oxidise atRAL to atRA - Gallus gallus
inferredFrom	[Reaction:R-HSA-5362564] ADH1A,1C,4 oxidise atROL to atRAL in vitro - Homo sapiens
input	[SimpleEntity:R-ALL-975599] atROL [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ADH1A,1C,4 oxidise atROL to atRAL in vitro
output	[SimpleEntity:R-ALL-975622] atRAL [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
precedingEvent	[Reaction:R-GGA-2453863] STRA6 transports atROL from extracellular region to cytosol - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5362564
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5365859] RA biosynthesis pathway
(precedingEvent)	[Reaction:R-GGA-5362522] ALDHs oxidise atRAL to atRA
(inferredTo)	[Reaction:R-HSA-5362564] ADH1A,1C,4 oxidise atROL to atRAL in vitro

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