Reactome | RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL

Schema > Reaction > Entries

RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL Show undefined attributes

catalystActivity	[CatalystActivity:10789311] all-trans-retinol dehydrogenase (NAD+) activity of RDH10,16,DHRS9,RDHE2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10789313
displayName	RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL
eventOf	[Pathway:R-GGA-5365859] RA biosynthesis pathway - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-5362522] ALDHs oxidise atRAL to atRA - Gallus gallus
inferredFrom	[Reaction:R-HSA-5362518] RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL - Homo sapiens
input	[SimpleEntity:R-ALL-975599] atROL [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL Multiple RDHs convert atROL into atRAL
output	[SimpleEntity:R-ALL-975622] atRAL [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
precedingEvent	[Reaction:R-GGA-2453863] STRA6 transports atROL from extracellular region to cytosol - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5362518
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5365859] RA biosynthesis pathway
(precedingEvent)	[Reaction:R-GGA-5362522] ALDHs oxidise atRAL to atRA
(inferredTo)	[Reaction:R-HSA-5362518] RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL

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