Reactome | NFKB1:MAP3K8:TNIP2 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-GGA-5684267] IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex - Gallus gallus [Reaction:R-GGA-5684275] IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 - Gallus gallus [Reaction:R-GGA-5684261] MAP3K8 is phosphorylated - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10761097
displayName	NFKB1:MAP3K8:TNIP2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-GGA-389388] MAP3K8 [cytosol] [EntityWithAccessionedSequence:R-GGA-451607] NFKB1 [cytosol] [EntityWithAccessionedSequence:R-GGA-451661] TNIP2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-451638] NFKB1:MAP3K8:TNIP2 [cytosol] - Homo sapiens
maxDepth	2
name	NFKB1:MAP3K8:TNIP2
producedByEvent	[Reaction:R-GGA-451634] NFKB p105, TPL2 (COT) and ABIN2 form a stable complex - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-451638
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-5684267] IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex [Reaction:R-GGA-5684275] IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 [Reaction:R-GGA-5684261] MAP3K8 is phosphorylated
(output)	[Reaction:R-GGA-451634] NFKB p105, TPL2 (COT) and ABIN2 form a stable complex
(inferredTo)	[Complex:R-HSA-451638] NFKB1:MAP3K8:TNIP2 [cytosol]