Reactome | Phosphorylation of L1 by ERK

Schema > Reaction > Entries

Phosphorylation of L1 by ERK Show undefined attributes

catalystActivity	[CatalystActivity:10738597] MAP kinase activity of p-T185,Y187-MAPK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10759899
displayName	Phosphorylation of L1 by ERK
eventOf	[Pathway:R-GGA-437239] Recycling pathway of L1 - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-445079] Phosphorylation of L1 by ERK - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-GGA-392743] L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] [EntityWithAccessionedSequence:R-GGA-109853] phospho-MAPK3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of L1 by ERK
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-GGA-445005] pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome]
precedingEvent	[Reaction:R-GGA-392749] Transport of L1 into endosomes - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-445079
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-437239] Recycling pathway of L1
(inferredTo)	[Reaction:R-HSA-445079] Phosphorylation of L1 by ERK

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