Reactome | CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol

Schema > Reaction > Entries

CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10759395] long-chain fatty acid transmembrane transporter activity of 4xPalmC-CD36 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10759397
displayName	CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol
eventOf	[Pathway:R-GGA-434313] Intracellular metabolism of fatty acids regulates insulin secretion - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-434382] ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A - Gallus gallus
inferredFrom	[Reaction:R-HSA-434381] CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-8954142] LCFA(-) [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol a long-chain fatty acid(out) = a long-chain fatty acid(in)
output	[SimpleEntity:R-ALL-8876730] LCFA(-) [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-434381
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-434313] Intracellular metabolism of fatty acids regulates insulin secretion
(precedingEvent)	[Reaction:R-GGA-434382] ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A
(inferredTo)	[Reaction:R-HSA-434381] CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol

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