Reactome | SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol

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SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10758667] D-glucose:sodium symporter activity of SLC5As, NAGLT1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10758669
displayName	SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol
eventOf	[Pathway:R-GGA-189200] Cellular hexose transport - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-429613] SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-70115] Glc [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol Co-transport (influx) of glucose and Na+ ions by SLC5As, NAGLT1
output	[SimpleEntity:R-ALL-70113] Glc [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-429613
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-189200] Cellular hexose transport
(inferredTo)	[Reaction:R-HSA-429613] SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol

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