Reactome | Interaction of Nectins with Afadin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10757245
displayName	Interaction of Nectins with Afadin
eventOf	[Pathway:R-GGA-418990] Adherens junctions interactions - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-419003] Interaction of Nectins with Afadin - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-418342] AFDN [cytosol] [DefinedSet:R-GGA-419017] Nectin [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of Nectins with Afadin
output	[Complex:R-GGA-419013] Nectin:afadin [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-419003
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-418990] Adherens junctions interactions
(inferredTo)	[Reaction:R-HSA-419003] Interaction of Nectins with Afadin

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