Reactome | OPN (osteopontin) degradation by MMP3, MMP7

Schema > Reaction > Entries

OPN (osteopontin) degradation by MMP3, MMP7 Show undefined attributes

catalystActivity	[CatalystActivity:10786649] metalloendopeptidase activity of MMP3, MMP7 [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10786651
displayName	OPN (osteopontin) degradation by MMP3, MMP7
eventOf	[Pathway:R-GGA-1474228] Degradation of the extracellular matrix - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4086205] OPN (osteopontin) degradation by MMP3, MMP7 - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-215967] SPP1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	OPN (osteopontin) degradation by MMP3, MMP7
output	[EntityWithAccessionedSequence:R-GGA-4093351] SPP1 [extracellular region] [EntityWithAccessionedSequence:R-GGA-4093349] SPP1 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-4086205
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1474228] Degradation of the extracellular matrix
(inferredTo)	[Reaction:R-HSA-4086205] OPN (osteopontin) degradation by MMP3, MMP7

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