Reactome | Sema4D in semaphorin signaling

Schema > Pathway > Entries

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826605
displayName	Sema4D in semaphorin signaling
eventOf	[Pathway:R-GGA-373755] Semaphorin interactions - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-GGA-416550] Sema4D mediated inhibition of cell attachment and migration - Gallus gallus [Pathway:R-GGA-416572] Sema4D induced cell migration and growth-cone collapse - Gallus gallus
inferredFrom	[Pathway:R-HSA-400685] Sema4D in semaphorin signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Sema4D in semaphorin signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-400685
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-373755] Semaphorin interactions
(inferredTo)	[Pathway:R-HSA-400685] Sema4D in semaphorin signaling

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