Reactome | PPARA:RXRA binds Corepressors of PPARA

Schema > BlackBoxEvent > Entries

PPARA:RXRA binds Corepressors of PPARA Show undefined attributes

catalystActivity	[CatalystActivity:10756739] transcription corepressor activity of Corepressors of PPARalpha [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10756741
displayName	PPARA:RXRA binds Corepressors of PPARA
eventOf	[Pathway:R-GGA-400206] Regulation of lipid metabolism by PPARalpha - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9734475] PPARA binds fibrates - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:422887] negative regulation of transcription initiation by RNA polymerase II
inferredFrom	[BlackBoxEvent:R-HSA-400183] PPARA:RXRA binds Corepressors of PPARA - Homo sapiens
input	[DefinedSet:R-GGA-400207] Corepressors of PPARalpha [nucleoplasm] [Complex:R-GGA-400138] PPARA:RXRA heterodimer [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-351643] TBL1XR1 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-351644] TBLX1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PPARA:RXRA binds Corepressors of PPARA
output	[Complex:R-GGA-400196] PPARA:RXRA:Corepressors [nucleoplasm]
precedingEvent	[Reaction:R-GGA-9734475] PPARA binds fibrates - Gallus gallus [Reaction:R-GGA-400204] PPARA binds RXRA - Gallus gallus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-400183
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-400206] Regulation of lipid metabolism by PPARalpha
(precedingEvent)	[Reaction:R-GGA-9734475] PPARA binds fibrates
(inferredTo)	[BlackBoxEvent:R-HSA-400183] PPARA:RXRA binds Corepressors of PPARA

Cite Us!