Reactome | Mitotic checkpoint complex [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-141410] MCC:APC/C complex [cytosol] - Gallus gallus [Complex:R-GGA-375305] Kinetochore [cytosol] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-141423] Binding of the MCC complex to the APC/C complex - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10740425
displayName	Mitotic checkpoint complex [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-GGA-141436] BUB1B [cytosol] [EntityWithAccessionedSequence:R-GGA-141416] BUB3 [cytosol] [EntityWithAccessionedSequence:R-GGA-141412] CDC20 [cytosol] [EntityWithAccessionedSequence:R-GGA-141400] MAD2L1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-141440] hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] - Homo sapiens [Complex:R-HSA-377882] Mitotic checkpoint complex [cytosol] - Homo sapiens
maxDepth	2
name	Mitotic checkpoint complex
producedByEvent	[Reaction:R-GGA-141437] Formation of the MCC complex - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-377882
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-141423] Binding of the MCC complex to the APC/C complex
(output)	[Reaction:R-GGA-141437] Formation of the MCC complex
(hasComponent)	[Complex:R-GGA-141410] MCC:APC/C complex [cytosol] [Complex:R-GGA-375305] Kinetochore [cytosol]
(inferredTo)	[Complex:R-HSA-141440] hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] [Complex:R-HSA-377882] Mitotic checkpoint complex [cytosol]