Reactome | spherical HDL and SR-BI receptor form a complex at the cell surface

Schema > Reaction > Entries

spherical HDL and SR-BI receptor form a complex at the cell surface Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10751691
displayName	spherical HDL and SR-BI receptor form a complex at the cell surface
eventOf	[Pathway:R-GGA-8964011] HDL clearance - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-349638] Disassembly of SR-BI-bound spherical HDL - Gallus gallus
inferredFrom	[Reaction:R-HSA-349637] spherical HDL and SR-BI receptor form a complex at the cell surface - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-349415] SCARB1 [plasma membrane] [Complex:R-GGA-265523] spherical HDL [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	spherical HDL and SR-BI receptor form a complex at the cell surface
output	[Complex:R-GGA-349649] spherical HDL:SR-BI complex [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-349637
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-8964011] HDL clearance
(precedingEvent)	[Reaction:R-GGA-349638] Disassembly of SR-BI-bound spherical HDL
(inferredTo)	[Reaction:R-HSA-349637] spherical HDL and SR-BI receptor form a complex at the cell surface

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