Reactome | BRIP1 (FANCJ) helicase functions in direct unwinding of DNA

Schema > Reaction > Entries

authored	[InstanceEdit:209713] Saxena, A, 2008-01-04 18:30:50
catalystActivity	[CatalystActivity:265981] DNA helicase activity of FANCJ (BRIP1), Fanconi anemia group J protein homolog [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:265962] Saxena, A, 2008-04-21 13:32:36
dbId	265894
displayName	BRIP1 (FANCJ) helicase functions in direct unwinding of DNA
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
eventOf	[Pathway:R-GGA-351465] Fanconi Anemia Pathway in DNA repair - Gallus gallus
input	[OtherEntity:R-ALL-75155] 3' ends of DNA double strand break [nucleoplasm] [OtherEntity:R-ALL-169515] Replication Fork [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:265793] The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	BRIP1 (FANCJ) helicase functions in direct unwinding of DNA
output	[OtherEntity:R-ALL-265971] DNA repair intermediates [nucleoplasm]
precedingEvent	[Reaction:R-GGA-217150] Monoubiquitination of FancD2 - Gallus gallus
releaseDate	2009-06-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-265894
summation	[Summation:265844] BRIP1, a DNA helicase also known as FANCJ, provides evidence...

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