Reactome | Deacetylation of cohesin

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10611692] histone deacetylase activity of HDAC8 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10611700
displayName	Deacetylation of cohesin
eventOf	[Pathway:R-GGA-2500257] Resolution of Sister Chromatid Cohesion - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2545253] Deacetylation of cohesin - Homo sapiens
input	2 × [SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [Complex:R-GGA-2484812] p-Ac-Cohesin:PDS5:WAPAL [cytosol]
isInDisease	false
isInferred	true
name	Deacetylation of cohesin
output	2 × [SimpleEntity:R-ALL-76183] Ac-CoA [cytosol] [Complex:R-GGA-2545249] p-Cohesin:PDS5:WAPAL [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2545253
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-2500257] Resolution of Sister Chromatid Cohesion
(inferredTo)	[Reaction:R-HSA-2545253] Deacetylation of cohesin