Reactome | Antagonism of Activin by Follistatin

Schema > Pathway > Entries

compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10827499
displayName	Antagonism of Activin by Follistatin
eventOf	[Pathway:R-GGA-1502540] Signaling by Activin - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-2473186] FSTL3 binds Activin - Gallus gallus [Reaction:R-GGA-2473184] Follistatin (FST) binds Activin - Gallus gallus
inferredFrom	[Pathway:R-HSA-2473224] Antagonism of Activin by Follistatin - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Antagonism of Activin by Follistatin
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-2473224
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-1502540] Signaling by Activin
(inferredTo)	[Pathway:R-HSA-2473224] Antagonism of Activin by Follistatin

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