Reactome | SCARB1 (SR-BI, CLA-1) binds ligands

Schema > Reaction > Entries

SCARB1 (SR-BI, CLA-1) binds ligands Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10780754
displayName	SCARB1 (SR-BI, CLA-1) binds ligands
eventOf	[Pathway:R-GGA-3000471] Scavenging by Class B Receptors - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-GGA-2512800] SCARB1:ligand is endocytosed - Gallus gallus
inferredFrom	[Reaction:R-HSA-2197646] SCARB1 (SR-BI, CLA-1) binds ligands - Homo sapiens
input	[DefinedSet:R-GGA-2197637] Ligands of SCARB1 [extracellular region] [EntityWithAccessionedSequence:R-GGA-349415] SCARB1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	SCARB1 (SR-BI, CLA-1) binds ligands
output	[Complex:R-GGA-2197639] SCARB1:Ligand [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2197646
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-3000471] Scavenging by Class B Receptors
(precedingEvent)	[BlackBoxEvent:R-GGA-2512800] SCARB1:ligand is endocytosed
(inferredTo)	[Reaction:R-HSA-2197646] SCARB1 (SR-BI, CLA-1) binds ligands

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