Reactome | MFAP2, MFAP5 bind microfibrils

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10779226
displayName	MFAP2, MFAP5 bind microfibrils
eventOf	[Pathway:R-GGA-1566948] Elastic fibre formation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2129385] MFAP2, MFAP5 bind microfibrils - Homo sapiens
input	[CandidateSet:R-GGA-2159839] Fibrillin 1,2,(3) [extracellular region] [DefinedSet:R-GGA-2396477] MFAP2, MFAP5 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	MFAP2, MFAP5 bind microfibrils
output	[Complex:R-GGA-2396329] Fibrilins:MFAP2,MFAP5 [extracellular region]
precedingEvent	[Polymerisation:R-GGA-2129362] Fibrillin microfibril assembly - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2129385
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-1566948] Elastic fibre formation
(inferredTo)	[Reaction:R-HSA-2129385] MFAP2, MFAP5 bind microfibrils

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