Reactome | Caspase mediated cleavage of HIP-55

Schema > Reaction > Entries

Caspase mediated cleavage of HIP-55 Show undefined attributes

catalystActivity	[CatalystActivity:10748292] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10748997
displayName	Caspase mediated cleavage of HIP-55
eventOf	[Pathway:R-GGA-264870] Caspase-mediated cleavage of cytoskeletal proteins - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-202966] Caspase mediated cleavage of HIP-55 - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-202880] SH3GLB2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Caspase mediated cleavage of HIP-55
output	[EntityWithAccessionedSequence:R-GGA-202925] SH3GLB2 [cytosol] [EntityWithAccessionedSequence:R-GGA-202933] SH3GLB2 [cytosol]
precedingEvent	[Reaction:R-GGA-114252] Cleavage of Procaspase-3 by the apoptosome - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-202966
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-264870] Caspase-mediated cleavage of cytoskeletal proteins
(inferredTo)	[Reaction:R-HSA-202966] Caspase mediated cleavage of HIP-55

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