Reactome | Cross-linking of FCGRIA with IgG-coated Ag

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10778161
displayName	Cross-linking of FCGRIA with IgG-coated Ag
eventOf	[Pathway:R-GGA-2029481] FCGR activation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2029455] Cross-linking of FCGRIA with IgG-coated Ag - Homo sapiens
input	[Complex:R-GGA-173552] Antigen:IgG [plasma membrane] [Complex:R-GGA-2029093] FCGRIA:CD3G homodimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Cross-linking of FCGRIA with IgG-coated Ag
output	[Complex:R-GGA-2029132] IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2029455
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-2029481] FCGR activation
(inferredTo)	[Reaction:R-HSA-2029455] Cross-linking of FCGRIA with IgG-coated Ag

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