Reactome | Beta-catenin translocates to the nucleus

Schema > BlackBoxEvent > Entries

Beta-catenin translocates to the nucleus Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10748411
displayName	Beta-catenin translocates to the nucleus
eventOf	[Pathway:R-GGA-201681] TCF dependent signaling in response to WNT - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-GGA-201722] Formation of the beta-catenin:TCF transactivating complex - Gallus gallus [Reaction:R-GGA-3772430] CTNNBIP1 binds beta-catenin - Gallus gallus [Reaction:R-GGA-5368580] CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression - Gallus gallus [Reaction:R-GGA-5626938] Beta-catenin binds SOX proteins - Gallus gallus [Reaction:R-GGA-3769383] CBY1 binds beta-catenin - Gallus gallus [Reaction:R-GGA-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:436450] regulation of canonical Wnt signaling pathway
inferredFrom	[BlackBoxEvent:R-HSA-201669] Beta-catenin translocates to the nucleus - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-448839] CTNNB1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Beta-catenin translocates to the nucleus
output	[EntityWithAccessionedSequence:R-GGA-3451168] CTNNB1 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-201669
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-201681] TCF dependent signaling in response to WNT
(precedingEvent)	[Pathway:R-GGA-201722] Formation of the beta-catenin:TCF transactivating complex [Reaction:R-GGA-3772430] CTNNBIP1 binds beta-catenin [Reaction:R-GGA-5368580] CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression [Reaction:R-GGA-5626938] Beta-catenin binds SOX proteins [Reaction:R-GGA-3769383] CBY1 binds beta-catenin [Reaction:R-GGA-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF
(inferredTo)	[BlackBoxEvent:R-HSA-201669] Beta-catenin translocates to the nucleus