Reactome | p75NTR interacts with RIP2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10746165
displayName	p75NTR interacts with RIP2
eventOf	[Pathway:R-GGA-209543] p75NTR recruits signalling complexes - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-193656] p75NTR interacts with RIP2 - Homo sapiens
input	[Complex:R-GGA-205123] mature NGF homodimer:p75NTR [plasma membrane] [EntityWithAccessionedSequence:R-GGA-168402] RIPK2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p75NTR interacts with RIP2
output	[Complex:R-GGA-209578] NGF:p75NTR:RIP2 [plasma membrane]
precedingEvent	[Reaction:R-GGA-193653] NGF homodimer binds to p75NTR - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-193656
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-209543] p75NTR recruits signalling complexes
(inferredTo)	[Reaction:R-HSA-193656] p75NTR interacts with RIP2

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