Reactome | Hydrolysis of choloyl-CoA to cholate and CoASH

Schema > Reaction > Entries

Hydrolysis of choloyl-CoA to cholate and CoASH Show undefined attributes

catalystActivity	[CatalystActivity:10746095] acyl-CoA hydrolase activity of ACOT8 [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10746097
displayName	Hydrolysis of choloyl-CoA to cholate and CoASH
eventOf	[Pathway:R-GGA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH - Homo sapiens
input	[SimpleEntity:R-ALL-192356] choloyl-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Hydrolysis of choloyl-CoA to cholate and CoASH
output	[SimpleEntity:R-ALL-193451] CCA [peroxisomal matrix] [SimpleEntity:R-ALL-193514] CoA-SH [peroxisomal matrix]
precedingEvent	[Reaction:R-GGA-192341] Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-193385
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(inferredTo)	[Reaction:R-HSA-193385] Hydrolysis of choloyl-CoA to cholate and CoASH

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