Reactome | Signaling by NTRK1 (TRKA)

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Signaling by NTRK1 (TRKA) Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825897
displayName	Signaling by NTRK1 (TRKA)
eventOf	[Pathway:R-GGA-166520] Signaling by NTRKs - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-GGA-187015] Activation of TRKA receptors - Gallus gallus [Pathway:R-GGA-187687] Signalling to ERKs - Gallus gallus [Pathway:R-GGA-198203] PI3K/AKT activation - Gallus gallus [Pathway:R-GGA-198765] Signalling to ERK5 - Gallus gallus [Pathway:R-GGA-177504] Retrograde neurotrophin signalling - Gallus gallus [Pathway:R-GGA-198725] Nuclear Events (kinase and transcription factor activation) - Gallus gallus
inferredFrom	[Pathway:R-HSA-187037] Signaling by NTRK1 (TRKA) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	Signaling by NTRK1 (TRKA) NGF signalling via TRKA from the plasma membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-187037
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEncapsulatedEvent)	[Pathway:R-GGA-5673001] RAF/MAP kinase cascade [Pathway:R-GGA-193704] p75 NTR receptor-mediated signalling [Pathway:R-GGA-167060] NGF processing
(hasEvent)	[Pathway:R-GGA-166520] Signaling by NTRKs
(inferredTo)	[Pathway:R-HSA-187037] Signaling by NTRK1 (TRKA)

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