Reactome | ARSB hydrolyses C4S/C6S chains

Schema > Reaction > Entries

ARSB hydrolyses C4S/C6S chains Show undefined attributes

catalystActivity	[CatalystActivity:10773482] N-acetylgalactosamine-4-sulfatase activity of ARSB:Ca2+ [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10774597
displayName	ARSB hydrolyses C4S/C6S chains
eventOf	[Pathway:R-GGA-2024101] CS/DS degradation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-1793209] HYAL1-4 hydrolyze chondroitin chains - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:21606] chondroitin sulfate proteoglycan catabolic process
inferredFrom	[Reaction:R-HSA-1793207] ARSB hydrolyses C4S/C6S chains - Homo sapiens
input	[DefinedSet:R-ALL-2065251] C4S/C6S chains [lysosomal lumen] [SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ARSB hydrolyses C4S/C6S chains
output	[SimpleEntity:R-ALL-2065239] Chondroitin chain [lysosomal lumen] [SimpleEntity:R-ALL-1606845] SO4(2-) [lysosomal lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1793207
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-2024101] CS/DS degradation
(precedingEvent)	[Reaction:R-GGA-1793209] HYAL1-4 hydrolyze chondroitin chains
(inferredTo)	[Reaction:R-HSA-1793207] ARSB hydrolyses C4S/C6S chains

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