Reactome | Telomere C-strand synthesis initiation

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Telomere C-strand synthesis initiation Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826073
displayName	Telomere C-strand synthesis initiation
eventOf	[Pathway:R-GGA-174417] Telomere C-strand (Lagging Strand) Synthesis - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-GGA-174411] Polymerase switching on the C-strand of the telomere - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-9668831] CST complex formation - Gallus gallus [Reaction:R-GGA-9668597] DNA polymerase:primase binds G-strand of the telomere - Gallus gallus [Reaction:R-GGA-174425] The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere - Gallus gallus [Reaction:R-GGA-174427] The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere - Gallus gallus
inferredFrom	[Pathway:R-HSA-174430] Telomere C-strand synthesis initiation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Telomere C-strand synthesis initiation
precedingEvent	[BlackBoxEvent:R-GGA-164617] Elongation of Extended Telomeric Chromosome End - Gallus gallus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-174430
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-174417] Telomere C-strand (Lagging Strand) Synthesis
(precedingEvent)	[Pathway:R-GGA-174411] Polymerase switching on the C-strand of the telomere
(inferredTo)	[Pathway:R-HSA-174430] Telomere C-strand synthesis initiation