Reactome | Transport and metabolism of PAPS

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Transport and metabolism of PAPS Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826069
displayName	Transport and metabolism of PAPS
eventOf	[Pathway:R-GGA-1630316] Glycosaminoglycan metabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:80798] 3'-phosphoadenosine 5'-phosphosulfate metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-GGA-9941470] SLC26A11 imports SO4(2-) and H+ into cytosol - Gallus gallus [Reaction:R-GGA-427555] SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol - Gallus gallus [Reaction:R-GGA-174392] PAPSS1,2 transfer SO4(2-) group to ATP to form APS - Gallus gallus [Reaction:R-GGA-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Gallus gallus [Reaction:R-GGA-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Gallus gallus
inferredFrom	[Pathway:R-HSA-174362] Transport and metabolism of PAPS - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Transport and metabolism of PAPS
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-174362
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEncapsulatedEvent)	[Pathway:R-GGA-5173105] O-linked glycosylation [Pathway:R-GGA-156580] Phase II - Conjugation of compounds [Pathway:R-GGA-2022928] HS-GAG biosynthesis [Pathway:R-GGA-1638074] Keratan sulfate/keratin metabolism [Pathway:R-GGA-2022923] DS-GAG biosynthesis [Pathway:R-GGA-2022870] CS-GAG biosynthesis
(hasEvent)	[Pathway:R-GGA-1630316] Glycosaminoglycan metabolism
(inferredTo)	[Pathway:R-HSA-174362] Transport and metabolism of PAPS

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