Reactome | Degradation of multiubiquitinated Cdh1

Schema > BlackBoxEvent > Entries

Degradation of multiubiquitinated Cdh1 Show undefined attributes

catalystActivity	[CatalystActivity:10732520] endopeptidase activity of 26S proteasome [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10743426
displayName	Degradation of multiubiquitinated Cdh1
eventOf	[Pathway:R-GGA-174084] Autodegradation of Cdh1 by Cdh1:APC/C - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-174058] Degradation of multiubiquitinated Cdh1 - Homo sapiens
input	[Complex:R-GGA-174068] multiubiquitinated Cdh1 associated with APC/C [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Degradation of multiubiquitinated Cdh1
output	[Complex:R-GGA-174109] phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] 3 × [DefinedSet:R-GGA-68524] Ub [nucleoplasm]
precedingEvent	[Reaction:R-GGA-174057] Multiubiquitination of APC/C-associated Cdh1 - Gallus gallus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-174058
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-174084] Autodegradation of Cdh1 by Cdh1:APC/C
(inferredTo)	[BlackBoxEvent:R-HSA-174058] Degradation of multiubiquitinated Cdh1

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