Reactome | D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate

Schema > Reaction > Entries

D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate Show undefined attributes

catalystActivity	[CatalystActivity:10734357] transketolase activity of TKT dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10741714
displayName	D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate
eventOf	[Pathway:R-GGA-163754] Insulin effects increased synthesis of Xylulose-5-Phosphate - Gallus gallus [Pathway:R-GGA-71336] Pentose phosphate pathway - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-163751] D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate - Homo sapiens
input	[SimpleEntity:R-ALL-29512] Fru(6)P [cytosol] [SimpleEntity:R-ALL-29578] GA3P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TKT dimer transfers two-carbon ketol group onto GA3P
output	[SimpleEntity:R-ALL-29878] E4P [cytosol] [SimpleEntity:R-ALL-29790] XY5P [cytosol]
precedingEvent	[Reaction:R-GGA-70471] GPI dimer isomerizes G6P - Gallus gallus [Reaction:R-GGA-70454] TPI1 dimer isomerizes DHAP to GA3P - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-163751
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-163754] Insulin effects increased synthesis of Xylulose-5-Phosphate [Pathway:R-GGA-71336] Pentose phosphate pathway
(inferredTo)	[Reaction:R-HSA-163751] D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate

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