Reactome | Cytosolic sulfonation of small molecules

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Cytosolic sulfonation of small molecules Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825793
displayName	Cytosolic sulfonation of small molecules
eventOf	[Pathway:R-GGA-156580] Phase II - Conjugation of compounds - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:80798] 3'-phosphoadenosine 5'-phosphosulfate metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-158468] SULT1A1 dimer sulfonates PARA to PARA-SO4 - Gallus gallus [Reaction:R-GGA-158860] SULT1A1 dimer sulfonates NHABP - Gallus gallus [Reaction:R-GGA-158849] Phenol can form a sulfate conjugate - Gallus gallus [Reaction:R-GGA-159358] SULT1A3,4 dimers sulfate DA to DAOS - Gallus gallus [Reaction:R-GGA-176474] 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP - Gallus gallus [Reaction:R-GGA-176585] 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP - Gallus gallus [Reaction:R-GGA-176646] p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP - Gallus gallus [Reaction:R-GGA-176669] N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP - Gallus gallus [Reaction:R-GGA-176609] cholesterol + PAPS => cholesterol sulfate + PAP - Gallus gallus [Reaction:R-GGA-176494] SULTs transfer (SO4)2- group to 27HCHOL - Gallus gallus [Reaction:R-GGA-176517] SULTs transfer (SO4)2- group to PREG - Gallus gallus [Reaction:R-GGA-176664] estrone + PAPS => estrone 3-sulfate + PAP - Gallus gallus [Reaction:R-GGA-176631] dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP - Gallus gallus [Reaction:R-GGA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Gallus gallus [Reaction:R-GGA-176588] lithocholate + PAPS => lithocholate sulfate + PAP - Gallus gallus [Reaction:R-GGA-176604] taurolithocholate + PAPS => taurolithocholate sulfate + PAP - Gallus gallus [Reaction:R-GGA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Gallus gallus [Reaction:R-GGA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2 - Gallus gallus
inferredFrom	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Cytosolic sulfonation of small molecules
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-156584
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-156580] Phase II - Conjugation of compounds
(inferredTo)	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules

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