Reactome | Trimerization of TRAIL:TRAIL receptor complex

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Trimerization of TRAIL:TRAIL receptor complex Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10740103
displayName	Trimerization of TRAIL:TRAIL receptor complex
eventOf	[Pathway:R-GGA-75158] TRAIL signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-141139] Trimerization of TRAIL:TRAIL receptor complex - Homo sapiens
input	3 × [Complex:R-GGA-5637465] TNFSF10:TNFRSF10A,B [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Trimerization of TRAIL:TRAIL receptor complex Trimerization of TNFSF10:TNFRSF10A,TNFRSF10B Trimerization of TNFSF10:DR4,DR5
output	[Complex:R-GGA-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane]
precedingEvent	[Reaction:R-GGA-75238] TRAIL binds TRAIL receptors - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-141139
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-75158] TRAIL signaling
(inferredTo)	[Reaction:R-HSA-141139] Trimerization of TRAIL:TRAIL receptor complex

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