Reactome | dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane]

Schema > Complex > Entries

dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane] Show undefined attributes

compartment	[Compartment:17906] mitochondrial outer membrane
componentOf	[Complex:R-GGA-1227868] dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/or IKK epsilon: IRF3 [mitochondrial outer membrane] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-1227863] Recruitment of IRF to activated TBK1/IKK epsilon - Gallus gallus
created	[InstanceEdit:1227896] Shamovsky, V, 2011-03-10
dbId	1227865
displayName	dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane]
hasComponent	2 × [DefinedSet:R-GGA-1227880] activated TBK1/IKK epsilon [mitochondrial outer membrane] [CandidateSet:R-GGA-1227873] dsRNA:MDA5:IPS1:K63-linked polyubiquitin TRAF3/ or TRAF6 [mitochondrial outer membrane] 2 × [EntityWithAccessionedSequence:R-GGA-1227864] TANK [mitochondrial outer membrane]
inDisease	false
isChimeric	false
maxDepth	7
modified	[InstanceEdit:9014711] Shamovsky, Veronica, 2017-08-02
name	dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon
producedByEvent	[Reaction:R-GGA-1227881] Phosphorylation and release of IRF3 - Gallus gallus [Reaction:R-GGA-1227885] TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation - Gallus gallus
relatedSpecies	[Species:9014381] Infectious bronchitis virus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-1227865
updateTrackers	[UpdateTracker:9892692] Update Tracker - [Complex:1227865] dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane] - v54:[updateContainedComponent] [UpdateTracker:9897448] Update Tracker - [Complex:1227865] dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane] - v62:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9892692] Update Tracker - [Complex:1227865] dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane] - v54:[updateContainedComponent] [UpdateTracker:9897448] Update Tracker - [Complex:1227865] dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/IKK epsilon [mitochondrial outer membrane] - v62:[updateContainedComponent]
(output)	[Reaction:R-GGA-1227885] TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation [Reaction:R-GGA-1227881] Phosphorylation and release of IRF3
(input)	[Reaction:R-GGA-1227863] Recruitment of IRF to activated TBK1/IKK epsilon
(hasComponent)	[Complex:R-GGA-1227868] dsRNA:MDA5:IPS1:K63 pUb-TRAF3/or TRAF6:TANK:activated TBK1/or IKK epsilon: IRF3 [mitochondrial outer membrane]

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