Reactome | NLRX1 inhibits IPS1 signaling

Schema > Reaction > Entries

authored	[InstanceEdit:1168652] Shamovsky, V, 2011-01-04
category	binding
compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:1227707] Shamovsky, V, 2011-03-10
dbId	1227698
displayName	NLRX1 inhibits IPS1 signaling
edited	[InstanceEdit:1280191] Shamovsky, V, 2011-05-11
eventOf	[Pathway:R-GGA-1227888] Negative Regulation of MDA5 signaling - Gallus gallus
inferredFrom	[Reaction:R-HSA-936564] NLRX1 inhibits MAVS-DDX58 interaction - Homo sapiens
input	[EntityWithAccessionedSequence:R-GGA-1227704] IPS-1 [mitochondrial outer membrane] [EntityWithAccessionedSequence:R-GGA-1227689] NLRX1 [mitochondrial outer membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:936540] NLRX1 is a regulator of mitochondrial antiviral immunity
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NLRX1 inhibits IPS1 signaling
output	[Complex:R-GGA-1227684] IPS1: NLRX1 [mitochondrial outer membrane]
releaseDate	2011-06-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1295492] Garapati, P V, 2011-05-16
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1227698
summation	[Summation:1267844] NLRX1 is a member of nucleotide-binding domain and leucine-r...

(hasEvent)	[Pathway:R-GGA-1227888] Negative Regulation of MDA5 signaling
(inferredTo)	[Reaction:R-HSA-936564] NLRX1 inhibits MAVS-DDX58 interaction

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