Reactome | Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer

Schema > Reaction > Entries

Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10738496
displayName	Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer
eventOf	[Pathway:R-GGA-73817] Purine ribonucleoside monophosphate biosynthesis - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-73815] 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate - Gallus gallus
inferredFrom	[Reaction:R-HSA-111289] Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer - Homo sapiens
input	[Complex:R-GGA-73789] PPAT tetramer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer
output	2 × [Complex:R-GGA-73790] PPAT dimer [cytosol]
regulatedBy	[PositiveRegulation:R-GGA-420919] Positive regulation by 'PRPP [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-111289
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-73817] Purine ribonucleoside monophosphate biosynthesis
(precedingEvent)	[Reaction:R-GGA-73815] 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate
(inferredTo)	[Reaction:R-HSA-111289] Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer

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