Reactome | Degradation of CRY and PER proteins

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650760
displayName	Degradation of CRY and PER proteins
eventOf	[TopLevelPathway:R-DRE-9909396] Circadian clock - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-DRE-9934893] Proteolysis of K48polyUb-K,p-S-PER1,2,3 - Danio rerio
inferredFrom	[Pathway:R-HSA-9932298] Degradation of CRY and PER proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Degradation of CRY and PER proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9932298
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DRE-9909396] Circadian clock
(inferredTo)	[Pathway:R-HSA-9932298] Degradation of CRY and PER proteins

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