Reactome | OPTN binds ATG9A

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OPTN binds ATG9A Show undefined attributes

category	binding
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:5679192] phagophore assembly site membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10643652
displayName	OPTN binds ATG9A
eventOf	[Pathway:R-DRE-5205685] PINK1-PRKN Mediated Mitophagy - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9840807] OPTN binds ATG9A - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-5671732] atg9a [phagophore assembly site membrane] [Complex:R-DRE-9824890] p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	OPTN binds ATG9A
output	[Complex:R-DRE-9840806] ATG9A:p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]
precedingEvent	[Reaction:R-DRE-9824897] p-S-TBK1 phosphorylates OPTN - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9840807
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5205685] PINK1-PRKN Mediated Mitophagy
(inferredTo)	[Reaction:R-HSA-9840807] OPTN binds ATG9A