Reactome | Nuclear events mediated by NFE2L2

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Nuclear events mediated by NFE2L2 Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649986
displayName	Nuclear events mediated by NFE2L2
eventOf	[Pathway:R-DRE-9755511] KEAP1-NFE2L2 pathway - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DRE-9762114] GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 - Danio rerio [Reaction:R-DRE-9796067] PRKAA2 phosphorylates nuclear NFE2L2 - Danio rerio [BlackBoxEvent:R-DRE-9796047] PRKAA2 regulated nuclear export of NFE2L2 - Danio rerio [Pathway:R-DRE-9818027] NFE2L2 regulating anti-oxidant/detoxification enzymes - Danio rerio
inferredFrom	[Pathway:R-HSA-9759194] Nuclear events mediated by NFE2L2 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Nuclear events mediated by NFE2L2
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9759194
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9755511] KEAP1-NFE2L2 pathway
(inferredTo)	[Pathway:R-HSA-9759194] Nuclear events mediated by NFE2L2

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