Reactome | EDNRA binds EDNs

Schema > Reaction > Entries

EDNRA binds EDNs Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10641364
displayName	EDNRA binds EDNs
eventOf	[Pathway:R-DRE-375276] Peptide ligand-binding receptors - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9731924] EDNRA binds EDNs - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-388549] ednraa [plasma membrane] [DefinedSet:R-DRE-388544] EDNs [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	EDNRA binds EDNs Endothelin receptor A bind endothelins
output	[Complex:R-DRE-9731930] EDNRA:EDNs [plasma membrane]
precedingEvent	[Reaction:R-DRE-8876868] ECE1 cleaves EDN1(53-90) - Danio rerio [Reaction:R-DRE-5694082] XK:KEL:Zn2+ cleaves EDN3 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9731924
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-375276] Peptide ligand-binding receptors
(inferredTo)	[Reaction:R-HSA-9731924] EDNRA binds EDNs

Cite Us!