Reactome | PRMT1 methylates ESRs

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PRMT1 methylates ESRs Show undefined attributes

catalystActivity	[CatalystActivity:10639366] protein methyltransferase activity of PRMT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10639368
displayName	PRMT1 methylates ESRs
eventOf	[Pathway:R-DRE-9009391] Extra-nuclear estrogen signaling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9021170] Estrogen stimulates dimerization of plasma membrane estrogen receptors - Danio rerio
inferredFrom	[Reaction:R-HSA-9632182] PRMT1 methylates ESRs - Homo sapiens
input	[SimpleEntity:R-ALL-5279190] AdoMet [cytoplasm] [CandidateSet:R-DRE-9021065] PalmS-ESRs [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PRMT1 methylates ESRs
output	[SimpleEntity:R-ALL-71285] AdoHcy [cytosol] [CandidateSet:R-DRE-9637789] Me-PalmS-ESRs [plasma membrane]
precedingEvent	[BlackBoxEvent:R-DRE-9021079] PalmS-ESRs:CAVs translocate to plasma membrane - Danio rerio
regulatedBy	[PositiveRegulation:9632181] Positive regulation by 'ESTG [extracellular region]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9632182
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9009391] Extra-nuclear estrogen signaling
(precedingEvent)	[Reaction:R-DRE-9021170] Estrogen stimulates dimerization of plasma membrane estrogen receptors
(inferredTo)	[Reaction:R-HSA-9632182] PRMT1 methylates ESRs