Reactome | MAPK1 or MAPK3 phosphorylates NCF1 at Ser345

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MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 Show undefined attributes

catalystActivity	[CatalystActivity:10614984] MAP kinase activity of p-T,Y MAPK dimers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10639164
displayName	MAPK1 or MAPK3 phosphorylates NCF1 at Ser345
eventOf	[Pathway:R-DRE-5668599] RHO GTPases Activate NADPH Oxidases - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9626816] PIN1 binds p-S345-NCF1 - Danio rerio
inferredFrom	[Reaction:R-HSA-9626832] MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DRE-9626870] NCF1:NCF2:NCF4 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MAPK1 or MAPK3 phosphorylates NCF1 at Ser345
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-DRE-9626850] p-S-345-NCF1:NCF2:NCF4 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9626832
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5668599] RHO GTPases Activate NADPH Oxidases
(precedingEvent)	[Reaction:R-DRE-9626816] PIN1 binds p-S345-NCF1
(inferredTo)	[Reaction:R-HSA-9626832] MAPK1 or MAPK3 phosphorylates NCF1 at Ser345

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