Reactome | S1P binds S1PR3 in response to E2 stimulation

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10639143
displayName	S1P binds S1PR3 in response to E2 stimulation
eventOf	[Pathway:R-DRE-9009391] Extra-nuclear estrogen signaling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9625813] S1P binds S1PR3 in response to E2 stimulation - Homo sapiens
input	[SimpleEntity:R-ALL-5218688] S1P [plasma membrane] [EntityWithAccessionedSequence:R-DRE-419396] s1pr3a [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	S1P binds S1PR3 in response to E2 stimulation
output	[Complex:R-DRE-9625811] S1P:S1PR3 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9625813
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9009391] Extra-nuclear estrogen signaling
(inferredTo)	[Reaction:R-HSA-9625813] S1P binds S1PR3 in response to E2 stimulation

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