Reactome | FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650526
displayName	FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
eventOf	[Pathway:R-DRE-9614085] FOXO-mediated transcription - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-9617927] FOXO4 binds ATXN3 - Danio rerio
inferredFrom	[Pathway:R-HSA-9615017] FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9615017
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9614085] FOXO-mediated transcription
(inferredTo)	[Pathway:R-HSA-9615017] FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes

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