Reactome | Factor IIa inhibitors (peptide) bind IIa

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10638620
displayName	Factor IIa inhibitors (peptide) bind IIa
eventOf	[Pathway:R-DRE-9769739] Regulation of clotting cascade - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9603302] Factor IIa inhibitors (peptide) bind IIa - Homo sapiens
input	[Complex:R-DRE-156786] activated thrombin (factor IIa) [extracellular region] [DefinedSet:R-ALL-9603327] Factor IIa inhibitors (peptide) [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Factor IIa inhibitors (peptide) bind IIa
output	[Complex:R-DRE-9603322] Factor IIa inhibitors (peptide):IIa [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9603302
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9769739] Regulation of clotting cascade
(inferredTo)	[Reaction:R-HSA-9603302] Factor IIa inhibitors (peptide) bind IIa

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