Reactome | RHOJ GEFs activate RHOJ

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RHOJ GEFs activate RHOJ Show undefined attributes

catalystActivity	[CatalystActivity:10637798] guanyl-nucleotide exchange factor activity of RHOJ GEFs [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10637800
displayName	RHOJ GEFs activate RHOJ
eventOf	[Pathway:R-DRE-9013409] RHOJ GTPase cycle - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9017488] RHOJ GAPs stimulate RHOJ GTPase activity - Danio rerio
inferredFrom	[Reaction:R-HSA-9017491] RHOJ GEFs activate RHOJ - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-DRE-9017484] RHOJ:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	RHOJ GEFs activate RHOJ
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-DRE-9017485] RHOJ:GTP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9017491
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9013409] RHOJ GTPase cycle
(precedingEvent)	[Reaction:R-DRE-9017488] RHOJ GAPs stimulate RHOJ GTPase activity
(inferredTo)	[Reaction:R-HSA-9017491] RHOJ GEFs activate RHOJ

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