Reactome | G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12)

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G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10636243
displayName	G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12)
eventOf	[Pathway:R-DRE-416482] G alpha (12/13) signalling events - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8964333] G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) - Homo sapiens
input	[Complex:R-DRE-8964310] G alpha (12):BTK [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12)
output	[EntityWithAccessionedSequence:R-DRE-197948] BTK [cytosol] [Complex:R-DRE-114525] G-protein alpha (12):GTP [plasma membrane]
precedingEvent	[Reaction:R-DRE-8964246] BTK in G alpha (12)-BTK complex is activated - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8964333
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-416482] G alpha (12/13) signalling events
(inferredTo)	[Reaction:R-HSA-8964333] G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12)

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