Reactome | SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol

Schema > Reaction > Entries

SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10633106] D-glucose:sodium symporter activity of SLC5A1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10633108
displayName	SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol
eventOf	[Pathway:R-DRE-8981373] Intestinal hexose absorption - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-189242] SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region - Danio rerio
inferredFrom	[Reaction:R-HSA-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol - Homo sapiens
input	[DefinedSet:R-ALL-189227] Gal, Glc [extracellular region] 2 × [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol
output	[DefinedSet:R-ALL-189254] Gal, Glc [cytosol] 2 × [SimpleEntity:R-ALL-83910] Na+ [cytosol]
precedingEvent	[Reaction:R-DRE-189062] lactose + H2O => D-glucose + D-galactose - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8932955
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-8981373] Intestinal hexose absorption
(precedingEvent)	[Reaction:R-DRE-189242] SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region
(inferredTo)	[Reaction:R-HSA-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol

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