Reactome | PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE

Schema > Reaction > Entries

PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE Show undefined attributes

catalystActivity	[CatalystActivity:10633096] acyl-L-homoserine-lactone lactonohydrolase activity of PON1,2,3:2xCa2+ dimers [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10633098
displayName	PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE
eventOf	[Pathway:R-DRE-2142688] Synthesis of 5-eicosatetraenoic acids - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8932633] PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE - Homo sapiens
input	[SimpleEntity:R-ALL-8932801] 5-HETEL [extracellular region] [SimpleEntity:R-ALL-109276] H2O [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE
output	[SimpleEntity:R-ALL-8932804] 5-HETE [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8932633
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-2142688] Synthesis of 5-eicosatetraenoic acids
(inferredTo)	[Reaction:R-HSA-8932633] PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE

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