Reactome | Activated AR binds RUNX2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10632835
displayName	Activated AR binds RUNX2
eventOf	[Pathway:R-DRE-8940973] RUNX2 regulates osteoblast differentiation - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8877902] Activated AR binds RUNX2 - Homo sapiens
input	[Complex:R-DRE-5618087] AR:androgens [nucleoplasm] [CandidateSet:R-DRE-9007751] RUNX2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Activated AR binds RUNX2
output	[Complex:R-DRE-8877906] RUNX2:AR:androgen [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8877902
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-8940973] RUNX2 regulates osteoblast differentiation
(inferredTo)	[Reaction:R-HSA-8877902] Activated AR binds RUNX2

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