Reactome | MDP:NLRP1 binds ATP

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10589151
displayName	MDP:NLRP1 binds ATP
eventOf	[Pathway:R-DRE-844455] The NLRP1 inflammasome - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Polymerisation:R-DRE-844438] NLRP1 oligomerizes - Danio rerio
inferredFrom	[Reaction:R-HSA-879222] MDP:NLRP1 binds ATP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DRE-877370] MDP:NLRP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MDP:NLRP1 binds ATP
output	[Complex:R-DRE-879207] MDP:NLRP1:ATP [cytosol]
precedingEvent	[BlackBoxEvent:R-DRE-844447] NLRP1 senses MDP - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-879222
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-844455] The NLRP1 inflammasome
(precedingEvent)	[Polymerisation:R-DRE-844438] NLRP1 oligomerizes
(inferredTo)	[Reaction:R-HSA-879222] MDP:NLRP1 binds ATP

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