Reactome | SGT1 binds HSP90

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10589094
displayName	SGT1 binds HSP90
eventOf	[Pathway:R-DRE-844456] The NLRP3 inflammasome - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-873951] SGT1:HSP90 binds inactive NLRP3 - Danio rerio
inferredFrom	[Reaction:R-HSA-874087] SGT1 binds HSP90 - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-419617] HSP90AB1 [cytosol] [EntityWithAccessionedSequence:R-DRE-874107] sugt1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SGT1 binds HSP90
output	[Complex:R-DRE-874112] SUGT1:HSP90 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-874087
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-844456] The NLRP3 inflammasome
(precedingEvent)	[Reaction:R-DRE-873951] SGT1:HSP90 binds inactive NLRP3
(inferredTo)	[Reaction:R-HSA-874087] SGT1 binds HSP90

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