Reactome | 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]

Schema > Reaction > Entries

1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] Show undefined attributes

catalystActivity	[CatalystActivity:10565101] diacylglycerol O-acyltransferase activity of DGAT1 tetramer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10565103
displayName	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]
eventOf	[Pathway:R-DRE-75109] Triglyceride biosynthesis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-75900] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] - Homo sapiens
input	[SimpleEntity:R-ALL-76103] DAG [cytosol] [SimpleEntity:R-ALL-75967] FACoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] Conversion of Diacylglycerol to Triacylglycerol [DGAT1]
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-549167] TAG [cytosol]
precedingEvent	[Reaction:R-DRE-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-75900
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-75109] Triglyceride biosynthesis
(inferredTo)	[Reaction:R-HSA-75900] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]

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